Swissmedic Nr.: 12175051
Index: 01.07.10
Pharmacode: 978800
GTIN/EAN: 7680121750515
Markteintritt: k.a.
Kategorie: B Mehrmalige Abgabe auf eine ärztliche Verschreibung hin.





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Das mit DeinDoktor.ch erhaltene Rezept kann in einer der 1400 Schweizer Apotheken verwendet werden.
Wir organisieren mit einer unserer Partner-Apotheken eine Sendung Ihres Aphenylbarbit 15 mg/50 mg/100 mg, Tabletten (50 mg)'s gegen Unterschrift (24h)
oder dem Medikamenten-Taxi nach einer Online Sprechstunde, falls gewünscht.
Der Wirkstoff von Aphenylbarbit ist Phenobarbital, ein Vertreter aus der Gruppe der Barbiturate. Aphenylbarbit wird gegen Epilepsie und Krampfanfälle sowie als starkes Beruhigungsmittel eingesetzt.
Auf Verschreibung des Arztes oder der Ärztin.
Bei Vergiftungen mit zentral wirkenden Arzneimitteln (Schlaf-, Beruhigungs-, Anregungs- und Schmerzmittel) und Alkohol darf Aphenylbarbit nicht angewendet werden. Ebenso darf Aphenylbarbit bei schweren Störungen der Nieren-, Leber- und Lungenfunktionen, bei Herzmuskelschäden, bei Störungen des Abbaus des Blutfarbstoffes in der Leber sowie bei Arzneimittelabhängigkeit und Überempfindlichkeit gegen den Wirkstoff nicht angewendet werden.
Während der Behandlung darf kein Alkohol getrunken werden.
Es kann sich bei längerem Gebrauch eine Arzneimittelabhängigkeit entwickeln. Bei abruptem Absetzen nach Langzeitanwendung ist mit Entzugserscheinungen zu rechnen.
Dieses Arzneimittel kann auch bei bestimmungsgemässem Gebrauch das Reaktionsvermögen so weit verändern, dass die Fähigkeit zur aktiven Teilnahme am Strassenverkehr, insbesondere beim Autofahren, oder zum Bedienen von Maschinen beeinträchtigt wird. Dies gilt in verstärktem Masse im Zusammenwirken mit Alkohol.
Aphenylbarbit kann zu einer Vermehrung der arzneimittelabbauenden Fermente in der Leber führen. Dadurch wird der Abbau einiger Arzneimittel beschleunigt, was deren Wirkungsverlust bedeuten kann. Dies gilt beispielsweise für Präparate zur Empfängnisverhütung («Pille»), für Arzneimittel zur Hemmung der Blutgerinnung, für andere Arzneimittel gegen Epilepsie oder Krampfanfälle, für Antipilzmittel mit Griseofulvin sowie für Präparate, die bestimmte Hormone (wie Androgene, Gestagene, Östrogene und Glucocorticoide) enthalten.
Die Wirkung einiger Arzneimittel kann, bei gleichzeitiger Anwendung von Aphenylbarbit, verstärkt oder abgeschwächt werden. Ebenso beeinflussen eine Reihe von Präparaten die Wirkung von Aphenylbarbit. Wird z.B. Aphenylbarbit zusammen mit anderen Beruhigungsmitteln und/oder Alkohol angewendet, kann sich die zentral dämpfende Wirkung bedrohlich verstärken.
Eine geringe Anzahl von Patienten, die mit Antiepileptika wie Phenobarbital behandelt wurden, hatten Gedanken daran, sich selbst zu verletzen oder sich das Leben zu nehmen. Wenn Sie zu irgendeinem Zeitpunkt solche Gedanken haben, setzen Sie sich sofort mit Ihrem Arzt oder Ärztin in Verbindung.
Aufgrund der Möglichkeit einer Photosensibilisierung (erhöhte Lichtempfindlichkeit der Haut) ist während der Anwendung von Phenobarbital starke Sonnenbestrahlung zu vermeiden.
Informieren Sie Ihren Arzt oder Apotheker bzw. Ihre Ärztin oder Apothekerin, wenn Sie an anderen Krankheiten leiden, Allergien haben oder andere Arzneimittel (auch selbst gekaufte!) einnehmen oder äusserlich anwenden!
Die Anwendung von Aphenylbarbit während der Schwangerschaft kann verschiedene Entwicklungsstörungen beim ungeborenen Kind verursachen. Wenn Sie schwanger sind oder es werden möchten, müssen Sie dies unbedingt Ihrem Arzt bzw. Ihrer Ärztin mitteilen. Er wird den weiteren Verlauf der Behandlung mit Ihnen besprechen und Sie bei der Planung einer Schwangerschaft beraten. Teilen Sie Ihrem Arzt bzw. Ihrer Ärztin auch mit, wenn Sie Ihr Kind stillen möchten.
Die für Sie persönlich notwendige Menge wird von Ihrem Arzt bzw. von Ihrer Ärztin festgelegt. Die verordnete Dosis hängt von der zu behandelnden Krankheit ab. In der Regel erhalten Erwachsene zwischen 100-200 mg pro Tag.
Auf keinen Fall dürfen von Erwachsenen mehr als 600 mg Phenobarbital pro Tag eingenommen werden.
Die Anwendung von Aphenylbarbit wird bei Kindern und Jugendlichen nicht empfohlen. Falls Aphenylbarbit doch angewendet werden soll, muss die Dosierung individuell durch den Arzt bzw. die Ärztin erfolgen.
Aphenylbarbit wird häufig abends angewendet. Die Tabletten werden mit etwas Flüssigkeit eingenommen.
Ändern Sie nicht von sich aus die verschriebene Dosierung. Wenn Sie glauben, das Arzneimittel wirke zu schwach oder zu stark, so sprechen Sie mit Ihrem Arzt oder Apotheker bzw. Ihrer Ärztin oder Apothekerin.
Benommenheit, Müdigkeit, Schläfrigkeit, Antriebslosigkeit, verlangsamte Reaktionszeit, eingeschränktes Urteilsvermögen, Artikulationsstörungen und Schwindel. Da Aphenylbarbit ein Barbiturat mit langer Wirkungsdauer enthält, können diese Anzeichen einer allgemeinen Dämpfung bis zum nächsten Tag anhalten! Als weitere unerwünschte Wirkungen wurden Kopfschmerzen, Übelkeit, Erbrechen, Verstopfung und Schmerzzustände an Muskeln, Nerven und Gelenken beobachtet. Viele der genannten Nebenwirkungen können zu Beginn einer Behandlung stärker ausgeprägt sein.
Besonders bei Kindern und älteren Patienten können Barbiturate Erregungszustände auslösen (paradoxe Reaktionen mit Unruhe, Aggressivität und Verwirrung).
Allergische Überempfindlichkeitsreaktionen, vor allem in Form sehr verschiedenartiger Hautveränderungen, sind bekannt. In Einzelfällen können diese Hautreaktionen schwerwiegend sein. Informieren Sie unverzüglich Ihren Arzt bzw. Ihre Ärztin beim Auftreten von Hautveränderungen.
Wie bei jeder antiepileptischen Langzeittherapie empfehlen sich regelmässige Blutbildkontrollen, da in seltenen Fällen unter Phenobarbital Blutbildveränderungen aufgetreten sind.
Im Hinblick auf mögliche Störungen des Kalziumstoffwechsels werden ebenfalls regelmässige Kontrolluntersuchungen und ggf. die Behandlung mit Vitamin D empfohlen, u.a. bei Kindern.
Bei längerem Gebrauch in hohen Dosen kann sich eine Abhängigkeit entwickeln. Bei abruptem Absetzen nach Langzeitanwendung können Entzugssymptome auftreten, daher soll die Dosis allmählich reduziert werden.
Es wurden Fälle von Verringerungen der Knochendichte (Osteoporose bis hin zu Knochenbrüchen) berichtet. Bitte beraten Sie sich mit Ihrem Arzt oder Apotheker bzw. Ihrer Ärztin oder Apothekerin, wenn Sie Antiepileptika über eine lange Zeit anwenden, wenn bei Ihnen eine Osteoporose festgestellt wurde oder wenn Sie gleichzeitig Kortison oder andere Steroidhormone einnehmen.
Wenn Sie Nebenwirkungen bemerken, die hier nicht beschrieben sind, sollten Sie Ihren Arzt oder Apotheker bzw. Ihre Ärztin oder Apothekerin informieren.
Bei Raumtemperatur (15-25 °C), vor Licht geschützt und ausser Reichweite von Kindern aufbewahren.
Das Arzneimittel darf nur bis zu dem auf dem Behälter mit «EXP» bezeichneten Datum verwendet werden.
Weitere Auskünfte erteilt Ihnen Ihr Arzt oder Apotheker bzw. Ihre Ärztin oder Apothekerin. Diese Personen verfügen über die ausführliche Fachinformation.
Tabletten zu 15 mg, 50 mg und 100 mg enthalten 15 mg, 50 mg, 100 mg Phenobarbital sowie Hilfsstoffe.
12175 (Swissmedic)
In Apotheken nur gegen ärztliche Verschreibung.
Aphenylbarbit 15 mg: Packungen zu 30 und 100 Tabletten.
Aphenylbarbit 50 mg und 100 mg: Packungen zu 20 und 100 Tabletten (teilbar).
Streuli Pharma AG, 8730 Uznach
Diese Packungsbeilage wurde im September 2013 letztmals durch die Arzneimittelbehörde (Swissmedic) geprüft.

























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