CHF 41.65

1-24 hours

Delivery is possible through one of our partner pharmacies after consultation.

Swissmedic Nr.: 46638034
Index: 07.08.20

Pharmacode: 2185067
GTIN/EAN: 7680466380347
Markteintritt: 19.12.1986

Kategorie: B Mehrmalige Abgabe auf eine ärztliche Verschreibung hin.


Oestrogel® (0.6 mg)

Estradiol (G03CA03)

3x80 g

(0/5 , 1476)

Um Oestrogel® (0.6 mg) kaufen zu können, benötigen Sie zunächst ein Rezept. Bei Deindoktor.ch können Sie im Rahmen einer Online-Sprechstunde per Webcam, mit dem Artz Ihrer Wahl, ein elektronische Rezept erhalten.

Das mit DeinDoktor.ch erhaltene Rezept kann in einer der 1400 Schweizer Apotheken verwendet werden. Wir organisieren mit einer unserer Partner-Apotheken eine Sendung Ihres Oestrogel® (0.6 mg)'s gegen Unterschrift (24h) oder dem Medikamenten-Taxi nach einer Online Sprechstunde, falls gewünscht.

You can get more infos with the following doctors during an online consultation. They might prescribe you this medicament.
Dr. Kathrin Holderegger, Weinfelden (TG)
Generalist
Gynaecologist


Tariff:
First 10 minutes: CHF 32.12
Next 5 minutes: CHF 14.75
Day tarif
Dr. Tim Schäufele, Bern (BE)
Cardiologist
Generalist
Internist


Tariff:
First 10 minutes: CHF 32.91
Next 5 minutes: CHF 15.28
Day tarif
Your received prescription through DeinDoktor.ch is usable to get your medicaments in any of the 1400 Swiss pharmacies or in the Swiss online pharmacies. We can arrange with one of our pharmacy-partners a delivery against signature (24h) or medicament-taxi after an online-consultation.

Oestrogel ist ein Gel, das als Wirkstoff das Hormon Östradiol enthält; dieses ist mit dem natürlichen Hormon identisch. Das perkutane Gel ist eine Verabreichungsform, die es ermöglicht, dass das Hormon die Haut durchdringt und unter Umgehung des Magens und der Leber direkt in die Blutbahn gelangt.

Östradiol ist das weibliche Geschlechtshormon, das vom Beginn der Pubertät an bis zur Menopause von den Eierstöcken gebildet wird. Der Stillstand der Östradiolproduktion nach der Menopause (d.h. nach der letzten Regelblutung) ist eine natürliche Erscheinung, die bei allen Frauen, gewöhnlich zwischen dem 45. und 55. Lebensjahr auftritt. Sie kann aber auch bei jüngeren Frauen, deren Eierstöcke durch einen chirurgischen Eingriff entfernt wurden, auftreten. Östrogenmangel ist für die typischen Wechseljahrbeschwerden wie Hitzewallungen, nächtliches Schwitzen, Schlafstörungen und Stimmungsschwankungen verantwortlich. Bei manchen Frauen kommt es ausserdem zu Problemen mit der Kontrolle der Blasenfunktion und zu einer Trockenheit der Scheide, die Beschwerden oder Schmerzen beim Geschlechtsverkehr verursachen kann.

Bei einigen Frauen setzt auch ein fortschreitender Schwund der Knochenmasse ein, der längerfristig zu Osteoporose führen kann, wodurch sich das Risiko von Knochenbrüchen, insbesondere im Bereich von Wirbelsäule, Hüftgelenk und Handgelenk, erhöht.

Oestrogel ist auf Verschreibung des Arztes angezeigt zur:

  • Behandlung von Störungen, die durch einen durch die Menopause verursachten Estrogenmangel bedingt sind,
  • Vorbeugung oder Verlangsamung der Osteoporose, die durch Estrogenmangel in der Menopause verursacht sind, bei Patientinnen mit einem hohen Frakturrisiko bei denen eine Behandlung mit anderen Präparaten, die zur Osteoporose-Vorbeugung zugelassen sind, nicht in Betracht kommt.

Bei Frauen mit intaktem Uterus wird die Behandlung mit Oestrogel durch eine zusätzliche Gestagenbehandlung durchgeführt, d.h. der Arzt bzw. die Ärztin wird Ihnen ein zusätzliches Hormonpräparat verschreiben. Im Allgemeinen erfolgt nach jeder Gestagentherapie eine Abbruchblutung. Bei einer zyklischen Anwendung von Oestrogel muss das Gestagen während den letzten 12 Tagen der Behandlung mit Oestrogel eingenommen werden.

Eine Hormonersatztherapie kann mit erhöhten Risiken, wie Brustkrebs oder Gebärmutterkrebs, Herz- Kreislaufkrankheiten (z.B. Herzinfarkt), zerebrovaskuläre Ereignisse (Schlaganfall), venösen Thrombosen und Lungenembolien (Bildung von Blutgerinnsel in den Blutgefässen), verbunden werden.

Ihr Arzt bzw. Ihre Ärztin wird mit Ihnen diese Risiken besprechen und gegenüber dem erwarteten Nutzen abwiegen.

Oestrogel darf nicht angewendet werden:

  • wenn Sie früher einmal ungewöhnlich oder allergisch auf Estrogene oder einen anderen Bestandteil des Gels reagiert haben (siehe auch «Was ist in Oestrogel enthalten?»),
  • wenn Sie an Brustkrebs leiden, oder bei Ihnen ein solcher Verdacht auf Brustkrebs besteht,
  • wenn Sie an einem estrogen-abhängigen Tumor, wie Gebärmutterkrebs leiden oder bei Ihnen ein solcher Verdacht besteht,
  • unbehandelte Volumenzunahme der Gebärmutterschleimhaut,
  • wenn Sie ungeklärte vaginale Blutungen haben,
  • wenn Sie an einer schweren Lebererkrankung leiden,
  • wenn Sie an einer schweren Erkrankung der Blutgefässe leiden oder gelitten haben, die auf Blutgerinnselbildung beruht (Venenthrombose, Lungenembolie, Schlaganfall, Herzinfarkt)
  • wenn Sie an einer bestimmten Stoffwechselstörung (z.B. Porphyrie) leiden.

Oestrogel darf nicht angewendet werden wenn Sie schwanger sind, schwanger werden könnten, oder stillen.

Bei intaktem Uterus dürfen Sie Oestrogel nicht als Einzeltherapie verwenden (siehe «Was ist Oestrogel und wann wird es angewendet?»). In diesem Fall wird Ihnen Ihr Arzt bzw. Ihre Ärztin auch ein anderes Hormonpräparat verschreiben.

Vor und während der Behandlung sind regelmässige medizinische und gynäkologische Untersuchungen nötig. In regelmässigen Abständen wird Ihr Arzt bzw. Ihre Ärztin mit Ihnen den Nutzen und die Risiken einer Hormonersatztherapie besprechen, um festzustellen, ob Sie die Behandlung weiterführen oder beenden müssen.

In folgenden Fällen ist die Behandlung der Menopause nicht kontraindiziert, jedoch bedarf es einer speziellen Überwachung: Risikofaktoren für Brustkrebs (Mammakarzinom bei Verwandten ersten Grades), Volumenzunahme der Gebärmutterschleimhaut in der Anamnese, fibröse Tumore der Gebärmutter, Endometriose (Erkrankung charakterisiertdurch Gebärmutterschleimhaut ausserhalb der Gebärmutter), Risikofaktoren für eine thromboembolische Erkrankung, Störungen der Leber oder der Galle, Bluthochdruck, Diabetes, Migräne oder schwere Kopfschmerzen, Lupus Erythematodes (schwere Erkrankung, die vor allem die Haut betrifft), Epilepsie, Asthma, chronische Otitis.

Eine engmaschigere Überwachung ist erforderlich bei vorangegangenen oder bestehenden Gefässerkrankungen (Venenthrombose, Phlebitis), Sichelzellanämie, Nieren- oder Herzinsuffizienz, Gallenwegserkrankungen, Ödemen, anhaltenden Blutungen, Tetanie, Multiple Sklerose.

Gründe für einen sofortigen Abbruch der Behandlung: erste Anzeichen einer Venenentzündung mit Gerinnselbildung oder anderen Symptomen, die mit einer Gerinnselbildung in Zusammenhang gebracht werden können (zum Beispiel ungewohnte Schmerzen in den Beinen oder Schwellungen der Beine, stechende Schmerzen beim Atmen oder Husten unbekannter Ursache), zerebrovaskuläre Störungen, plötzliche Störungen der Wahrnehmung (zum Beispiel Sehstörungen, Hörstörungen), erstmaliges oder häufigeres Auftreten von ungewohnt starken migräneartiger Kopfschmerzen, signifikanter Blutdruckanstieg, Ikterus oder Verschlechterung der Leberfunktion, messbares Wachstum gutartiger Tumore der Uteruswand, Schwangerschaft oder Auftreten einer der Gegenanzeigen, die im Abschnitt «Wann darf Östrogel nicht angewendet werden?» aufgeführt sind.

In verschiedenen wissenschaftlichen Untersuchungen wurde berichtet, dass das Risiko für Brustkrebs bei Frauen, die eine Hormonsubstitutionstherapie länger als 5 Jahre anwenden, leicht erhöht ist. Dieses erhöhte Risiko nimmt in den ersten fünf Jahren nach dem Absetzen der Hormonsubstitution langsam ab und ist dann wieder vergleichbar mit demjenigen von Frauen, die keine Hormonsubstitutionstherapie erhalten haben.

Ihr Arzt bzw. Ihre Ärztin wird eine regelmässige medizinische Untersuchungder Brust vornehmen, vor allem bei vorausgegangener Krebserkrankung in Ihrer Familie oder wenn Sie Zysten oder Knoten an der Brust haben. Ihr Arzt bzw. Ihre Ärztin kann Ihnen auch eine Mammographie verschreiben. Berichten Sie Ihrem Arzt bzw. Ihrer Ärztin, wenn Sie während der Behandlung eine Veränderung an Ihrer Brust feststellen.

Bei Frauen mit intaktem Uterus ist bei einer Östrogen-Monotherapie das Risiko für ein Endometriumkarzinom gegenüber nicht behandelten Frauen erhöht und vermutlich abhängig von der Behandlungsdauer und der Östrogendosis. Das höchste Risiko scheint bei einer Langzeittherapie zu bestehen.

Bei Auftreten unregelmässiger, starker oder anhaltender Blutungen sprechen Sie bitte mit Ihrem Arzt, bevor Sie die Behandlung fortsetzen.

Aus einigen Studien ergibt sich ein Zusammenhang zwischen einer Langzeitanwendung einer Östrogen-Monotherapie und einem erhöhten Risiko für die Entwicklung eines Ovarialkarzinoms (Eierstockkrebs).

Im Gegensatz zu einer kombinierten Hormonsubstitutionsbehandlung wurde bei einer Östrogen-Monotherapie keinerlei Einfluss auf die Häufigkeit einer Koronaren Herzkrankheit (KHK) festgestellt. Allerdings wurde ein erhöhtes Schlaganfallrisiko sowohl unter kombinierter Hormonsubstitution als auch unter Östrogen-Monotherapie verzeichnet.

Bei Östrogenbehandlungen sowie bei kombinierten Östrogen-Gestagen-Behandlungen wurde ein erhöhtes Thromboserisiko beobachtet. Dieses erhöhte Risiko wurde nur bei Frauen beobachtet, die sich zum Zeitpunkt des Ereignisses in Hormonsubstitutionsbehandlung befanden, nicht bei Frauen, die sich zu einem früheren Zeitpunkt einer Hormonsubstitutionsbehandlung unterzogen hatten. Die bekannte Datenlage lässt vermuten, dass das Risiko in den ersten Behandlungsjahren erhöht ist. Im Falle einer Immobilisation (Bettlägerigkeit) oder einer geplanten Operation informieren Sie bitte Ihren Arzt. Bei jeder länger andauernden Immobilisation nach einer Operation muss die Behandlung bereits vorher vorübergehend unterbrochen werden, sofern es sich um eine geplante Operation handelt, und darf erst bei vollständiger Mobilisierung wieder aufgenommenwerden.

In seltenen Fällen wurden bei älteren Patientinnen in Langzeittherapie mit kombinierten Hormonsubstitutionspräparaten (Östrogen/Gestagen) Gedächtnisstörungen und eine Abnahme der geistigen Leistungsfähigkeit beobachtet.

Bei Patientinnen, die eine Schilddrüsen-Hormonersatztherapie anwenden, ist insbesondere in den ersten Behandlungsmonaten regelmässig die Schilddrüsenfunktion zu überwachen (Bestimmung des TSH-Werts). 

Machen Sie Ihren Arzt bzw. Ihre Ärztin auf alle Krankheiten, die während der Behandlung auftreten, aufmerksam.

Sprechen Sie mit Ihrem Arzt bzw. mit Ihrer Ärztin, wenn die Symptome des Estrogenmangels, die durch die Menopause bedingt sind, trotz der Behandlung weiterhin bestehen bleiben.

Informieren Sie Ihren Arzt oder Apotheker bzw. Ihre Ärztin oder Apothekerin, wenn Sie an anderen Krankheiten leiden, Allergien haben oder bevor andere Arzneimittel (auch selbstgekaufte!) einnehmen oder äusserlich anwenden und vor allem wenn Sie Antiepileptika wie Phenytoin oder Carbamazepin oder Barbiturate, Antibiotika wie Rifampicin, Rifabutin, oder Arzneimittel gegen AIDS wie Nevirapin und Efavirenz, Ritonavir und Nelfinavir und pflanzliche Präparate auf Basis von Johanniskraut (Hypericum), einnehmen. Diese Arzneimittel führen zu einer Wirkungsverminderung von Oestrogel und zu einer Veränderung des Blutungsprofils.

Informieren Sie Ihren Arzt, Apotheker bzw. Ihre Ärztin,Apothekerin, wenn Sie an anderen Krankheiten leiden, Allergien haben oder andere Arzneimittel (auch selbstgekaufte!) einnehmen oder äusserlich anwenden!

Oestrogel darf weder während der Schwangerschaft, noch in der Stillzeit angewendet werden.

Ausserdem gibt es in diesen Situationen keine medizinische Indikation für die Verwendung von Oestrogel oder eines anderen weiblichen Sexualhormons.

a) Dosierung

Bevor Sie die Behandlung beginnen, bestimmt der Arzt die niedrigste wirksame Dosis. Je nach Ihren Bedürfnissen legt er fest, mit welcher Gel-Dosis Sie beginnen und wie lange Sie Oestrogel anwenden. Oestrogel kann als zyklische oder als fortlaufende Therapie verordnet werden.

Zyklische Therapie:

In den ersten 25 Tagen des Monats wird täglich 1 Dosierungsmass oder 2 Hübe (=1 Dosis ) angewandt; danach wird eine Behandlungspause von 5 Tagen eingeschaltet, nachdem die Behandlung wiederholen.

Fortlaufende Therapie:

Den ganzen Monat hindurch wird täglich 1 Dosierungsmass oder 2 Hübe (=1 Dosis) angewandt.

Welches Behandlungsschema besser geeignet ist, wird Ihr Arzt entscheiden. Wenn er es in Ihrem Falle für notwendig erachtet, wird er Ihnen auch ein Gestagen verordnen, um damit die Wirkungen von Oestrogel auf die Gebärmutterschleimhaut auszugleichen (siehe «Wann ist bei der Anwendung von Oestrogel Vorsicht geboten?»). Ihr Arzt wird Sie ausserdem über alle wichtigen Einzelheiten, die Sie betreffen, informieren.

b) Richtige Handhabung

Die Anwendung erfolgt am günstigsten morgens nachdem Waschen; die tägliche Dosis entspricht eine Mittelrilledes Dosierungsmasses oder 2x Drücken (1 Dosis). Je nach Intensität der Symptome kann Ihr Arzt die Dosierung ändern.

Die Gel-Dosis wird auf ein grosses Hautarea auf die Arme und Schultern aufgetragen (nicht einmassieren).

Vor dem Bedecken mit Kleidung 2 Minuten trocknen lassen.

Oestrogel niemals auf die Brust oder in Brustbereich auftragen.

Die Applikationsstelle darf weder Rötungen noch Reizungen aufweisen.

Die Haut muss trocken und frei von öligen oder fettigen Rückständen sein, da dies das Eindringen des Hormons in die Haut verhindert.

Oestrogel farb- und geruchlos und hinterlässt auf der Kleidung keine Flecken.

Dispenser

Verschlusskappe entfernen, kleiner Stopfen wegnehmen. Flakon mit einer Hand ergreifen und andere Hand unter die Öffnung halten, um das Gel aufzunehmen. Pumpe ganz niederdrücken und mit der anderen Hand austretendes Gel aufnehmen, wie auf der Abbildung dargestellt.

Bei jedem Erstgebrauch eines Dispensers kann 1- bis 2 maliges Betätigen der Pumpe erforderlich sein, bis das Gel freigesetzt wird. Die erste Gel-Dosis kann ungenau bemessen sein; es wird deshalb empfohlen, sie zu verwerfen. Nach einem Monat mit einer Dosierung von 2 Hüben/Tag kann sich die abgegebene Gel-Dosis verringern: diese soll nicht mehr verwendet werden.

Nach jedem Gebrauch soll der kleine Stopfen, der bei der ersten Verwendung nach dem Abheben der Verschlusskappe entfernt wurde, wieder in die Mündung eingesetzt werden.

Ein Hub entspricht 1/2 Oestrogel-Dosis oder 1,25 g Gel.

Tube

Jede Tube wird in der Originalpackung mit einem mit Mittelrille versehenen Dosierungsmass geliefert. Oestrogel-Tube durch Einstechen der Verschlusskappe mit dem eigens dafür vorgesehenen Stopfen öffnen. Gel, wie auf der Abbildung dargestellt, durch leichten Druck auf die Tube in die Mittelrille des Dosierungsmasses geben: diese Menge entspricht einer Dosis Oestrogel (2,5 g Gel).

Ändern Sie nicht von sich aus die vom Arzt verschriebene Dosierung. Wenn Sie glauben, das Medikament wirke zu schwach oder zu stark, so sprechen Sie mit Ihrem Arzt oder Apotheker.

Machen Sie Ihren Arzt bzw. Ihre Ärztin auf jegliche Veränderungen, die Sie während der Behandlung feststellen, aufmerksam.

Konsultieren Sie unverzüglich Ihren Arzt bzw. Ihre Ärztin, wenn Sie eine der unerwünschte Wirkungen unter «Wann ist bei der Anwendung von Oestrogel Vorsicht geboten?» beobachten (siehe «Gründe für das sofortige Absetzen der Behandlung»).

Folgende unerwünschte Wirkungen können auftreten:

Gelegentlich Mammakarzinom, Kopfschmerzen, Migräne, Übelkeit, Unterleibsschmerzen, Blähungen, Gallensteine, Pigmentflecken im Gesicht, Spannungsgefühl in der Brust, Zwischenblutungen unterschiedlicher Stärke (Metrorrhagie, Schmierblutung), Veränderung der Scheidenflora, Volumenzunahme des Endometriums, Irritationen, Pruritus, Exanthem an der Applikationsstelle, Ödem, Schwere in den Beinen, Gewichtszunahme.

Selten Endometriumkarzinom, Schwindel, Schmerzen in den Beinen, Oberschenkeln oder im Brustkorb, plötzliche Atemnot, Husten mit blutigem Auswurf, erhöhter Puls oder Schwindel (Anzeichen für thromboembolische Störungen, Thrombose) Schlaganfall, Herzinfarkt, Verschlechterung der Leberfunktion, Cholestase, cholestatischer Ikterus, Auftreten von Hauterkrankungen mit Rötungen, Hautentzündungen, nicht karzinomatöse Veränderungen der Brust (z.B. Zysten), benigne Gebärmuttertumore, Schmerzen in den Beinen.

Sehr selten heftige und schwere allergische Reaktionen, Kontaktlinsenunverträglichkeit, Verschlechterung von Varizen, Blutdruckanstieg.

Wenn Sie Nebenwirkungen bemerken, die hier nicht beschrieben sind, sollten Sie Ihren Arzt, Apotheker bzw. Ihre Ärztin, Apothekerin informieren.

Oestrogel soll für Kinder unerreichbar aufbewahrt werden, und bei Raumtemperatur (unter 25 °C) zu lagern.

Das Medikament darf nur bis zu dem auf der Packung mit «EXP» bezeichneten Datum verwendet werden.

Weitere Auskünfte erteilt Ihnen Ihr Arzt oder Apotheker, derüber die ausführliche Fachinformation verfügt.

1 Dosierungsmass (2,5 g Gel) enthält 1,5 mg Estradiol (als Wirkstoff) und Hilfsstoffe von welchen 1 g Alkohol 95% (w/w).

1 Hub (1,25 g Gel) enthält 0,75 mg Estradiol und Hilfsstoffe von welchen 0.5 g Alkohol 95% (w/w).

46638 (Swissmedic).

In Apotheken, nur gegen ärztliches Rezept.

Tube zu 80 g mit einem Dosierungsmass.

Packungen von 1 und 3 Dispenser von 80 g. 

Vifor SA, 1752 Villars-sur-Glâne.

Diese Packungsbeilage wurde im September 2012 letztmals durch die Arzneimittelbehörde (Swissmedic) geprüft.

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