Swissmedic Nr.: 57455020
Index: 07.04.20
Pharmacode: 3259460
GTIN/EAN: 7680574550205
Markteintritt: 06.04.2006
Kategorie: B Mehrmalige Abgabe auf eine ärztliche Verschreibung hin.




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Tirosint enthält das synthetisch hergestellte Levothyroxin, welches mit dem natürlich von der Schilddrüse gebildeten Hormon völlig identisch ist.
Tirosint wird vor allem in den folgenden Fällen angewendet:
Eine erfolgreiche Behandlung setzt die regelmässige Einnahme des Arzneimittels voraus.
Auf Verschreibung des Arztes oder der Ärztin.
Tirosint darf nicht angewendet werden:
Es gibt keinen Nachweis, dass Schilddrüsenhormone bei Übergewicht von Patienten bzw. Patientinnen mit einer normalen Schilddrüsenfunktion eine gewichtsvermindernde Wirkung haben. Deshalb, und da höhere Dosen sehr schwerwiegende Nebenwirkungen verursachen können, ist Tirosint zur Behandlung von Übergewicht nicht geeignet und darf nicht angewendet werden.
Informieren Sie unbedingt ihren Arzt oder Ihre Ärztin, wenn Sie herzkrank oder Diabetiker sind oder einen zu hohen Blutdruck haben, damit Ihr Arzt oder Ihre Ärztin die Behandlung entsprechend einstellen kann.
Bei Unterfunktion der Hirnanhangsdrüse oder wenn die Nebenniere aus anderen Gründen eine ungenügende Leistung zeigt, wird Ihnen der Arzt oder die Ärztin wahrscheinlich zusätzlich eine Behandlung mit Nebennierenrinden-Hormonen verschreiben.
Informieren Sie Ihren Arzt oder Apotheker bzw. Ihre Ärztin oder Apothekerin, wenn Sie an
Während der Schwangerschaft und Stillzeit sollte die Einnahme von Tirosint nicht unterbrochen werden. Jedoch wird Ihr Arzt oder Ihre Ärztin entscheiden, ob und in welcher Dosierung Sie während einer Schwangerschaft oder während einer Stillzeit Tirosint einnehmen dürfen.
Die erforderliche tägliche Dosis ist individuell unterschiedlich und wird durch den Arzt oder die Ärztin anhand labordiagnostischer und klinischer Untersuchungen festgelegt. Um diese individuelle Behandlung optimal zu ermöglichen, stehen Kapseln in verschiedenen Dosierungen mit abgestuftem Gehalt von 13 bis 200 µg des Wirkstoffs zur Verfügung.
Die Anfangsdosis für Erwachsene beträgt in der Regel 25?50 µg täglich und wird jeweils in 2?4-wöchigen Abständen um 13?50 µg /Tag bis auf 100?200 µg /Tag bis zur Normalisierung des Stoffwechsels erhöht.
Die Funktion Ihrer Schilddrüse soll regelmässig und bei der Umstellung von einem anderen Levothyroxinpräparat durch Ihren Arzt bzw. Ihre Ärztin kontrolliert werden.
Bei älteren Patienten, Patienten mit Herzkrankheiten, schwerer Schilddrüsenunterfunktion oder anderen Stoffwechselstörungen ist die Anfangsdosis niedriger.
Bei Kindern wird die Dosis entsprechend dem Körpergewicht festgelegt. Je nach Erkrankung kann die Dosis auch höher sein.
Für Säuglinge unter 1 Jahr ist Tirosint nicht geeignet.
Halten Sie sich strikte an die vom Arzt bzw. von der Ärztin verordnete Dosis.
Eine erfolgreiche Behandlung setzt die regelmässige Einnahme des Präparates und eine optimale, auf die individuellen Bedürfnisse des Patienten abgestimmte Tagesdosis voraus. Bei weiter bestehenden Krankheitszeichen trotz mehrwöchiger Therapie sollte der Arzt oder die Ärztin aufgesucht werden, der/die gegebenenfalls über eine Erhöhung der Dosis entscheiden wird.
Bei Unterbruch oder vorzeitiger Beendigung der Behandlung kann es zum Wiederauftreten von Krankheitssymptomen kommen, deren Art von der jeweiligen Grunderkrankung abhängig ist.
Haben Sie versehentlich an einem Tag die Einnahme von Tirosint vergessen, so nehmen Sie am folgenden Tag nur Ihre normale Dosis ein.
Die gesamte Tagesdosis wird morgens nüchtern, mindestens ½ Stunde vor dem Frühstück unzerkaut mit etwas Flüssigkeit eingenommen.
Die Behandlung mit Tirosint erfolgt bei Schilddrüsenunterfunktion und Schilddrüsenoperation wegen eines bösartigen Tumors der Schilddrüse zeitlebens, bei gutartigem Kropf und zur Verhütung eines erneuten Kropfwachstums einige Monate oder Jahre bis zeitlebens.
Bei Begleittherapie zur Behandlung der Schilddrüsenüberfunktion erfolgt die Behandlung mit Tirosint entsprechend der Dauer der Behandlung mit einem hemmenden Arzneimittel.
Schilddrüsenfunktionstest: Einnahme über 14?28 Tage bis zur Durchführung des Szintigramms.
Ändern Sie nicht von sich aus die verschriebene Dosierung. Wenn Sie glauben, das Arzneimittel wirke zu schwach oder zu stark, so sprechen Sie mit Ihrem Arzt oder Apotheker bzw. Ihrer Ärztin oder Apothekerin.
Folgende Symptome können gelegentlich als Folge der stoffwechselsteigernden Wirkung von Tirosint, vor allem bei zu hoher Dosierung oder bei zu schneller Steigerung der Dosis zu Beginn der Behandlung auftreten:
Unruhe, übermässiger, rascher Herzschlag (Tachykardie), Herzrythmusstörungen, Schmerzen im Brustkorb (Angina pectoris), vermehrtes Schwitzen, Durchfall, Gewichtsabnahme, Zittern, Kopfschmerzen, Schlaflosigkeit.
In diesen Fällen sollten Sie Rücksprache mit dem Arzt bzw. der Ärztin nehmen. Unter Umständen wird Ihre Therapie geändert.
Wenn Sie Nebenwirkungen bemerken, die hier nicht beschrieben sind, sollten Sie Ihren Arzt oder Apotheker bzw. Ihre Ärztin oder Apothekerin informieren.
Tirosint sollte in der Originalverpackung, bei Raumtemperatur (15?25 °C) und vor Licht geschützt gelagert werden.
Arzneimittel ausser Reichweite von Kindern aufbewahren.
Das Arzneimittel darf nur bis zu dem auf dem Behälter mit «Exp» bezeichneten Datum verwendet werden.
Weitere Auskünfte erteilt Ihnen Ihr Arzt oder Apotheker bzw. Ihre Ärztin oder Apothekerin. Diese Personen verfügen über die ausführliche Fachinformation.
1 Kapsel Tirosint 13 µg enthält als Wirkstoff 13 µg Levothyroxin-Natrium sowie Hilfsstoffe.
1 Kapsel Tirosint 25 µg enthält als Wirkstoff 25 µg Levothyroxin-Natrium sowie Hilfsstoffe.
1 Kapsel Tirosint 50 µg enthält als Wirkstoff 50 µg Levothyroxin-Natrium sowie Hilfsstoffe.
1 Kapsel Tirosint 75 µg enthält als Wirkstoff 75 µg Levothyroxin-Natrium sowie Hilfsstoffe.
1 Kapsel Tirosint 88 µg enthält als Wirkstoff 88 µg Levothyroxin-Natrium sowie Hilfsstoffe.
1 Kapsel Tirosint 100 µg enthält als Wirkstoff 100 µg Levothyroxin-Natrium sowie Hilfsstoffe.
1 Kapsel Tirosint 112 µg enthält als Wirkstoff 112 µg Levothyroxin-Natrium sowie Hilfsstoffe.
1 Kapsel Tirosint 125 µg enthält als Wirkstoff 125 µg Levothyroxin-Natrium sowie Hilfsstoffe.
1 Kapsel Tirosint 137 µg enthält als Wirkstoff 137 µg Levothyroxin-Natrium sowie Hilfsstoffe.
1 Kapsel Tirosint 150 µg enthält als Wirkstoff 150 µg Levothyroxin-Natrium sowie Hilfsstoffe.
1 Kapsel Tirosint 175 µg enthält als Wirkstoff 175 µg Levothyroxin-Natrium sowie Hilfsstoffe.
1 Kapsel Tirosint 200 µg enthält als Wirkstoff 200 µg Levothyroxin-Natrium sowie Hilfsstoffe.
57455 (Swissmedic).
In Apotheken nur gegen ärztliche Verschreibung.
Tirosint 13 µg: Packung zu 50 und 100 Weichkapseln A markiert (in Blister).
Tirosint 25 µg: Packung zu 50 und 100 Weichkapseln E markiert (in Blister).
Tirosint 50 µg: Packung zu 50 und 100 Weichkapseln G markiert (in Blister).
Tirosint 75 µg: Packung zu 50 und 100 Weichkapseln H markiert (in Blister).
Tirosint 88 µg: Packung zu 50 und 100 Weichkapseln J markiert (in Blister).
Tirosint 100 µg: Packung zu 50 und 100 Weichkapseln K markiert (in Blister).
Tirosint 112 µg: Packung zu 50 und 100 Weichkapseln M markiert(in Blister).
Tirosint 125 µg: Packung zu 50 und 100 Weichkapseln N markiert (in Blister).
Tirosint 137 µg: Packung zu 50 und 100 Weichkapseln P markiert (in Blister).
Tirosint 150 µg: Packung zu 50 und 100 Weichkapseln S markiert (in Blister).
Tirosint 175 µg: Packung zu 50 und 100 Weichkapseln U markiert (in Blister).
Tirosint 200 µg: Packung zu 50 und 100 Weichkapseln Y markiert (in Blister).
IBSA Institut Biochimique SA, CH-6903 Lugano.
Diese Packungsbeilage wurde im November 2010 letztmals durch die Arzneimittelbehörde (Swissmedic) geprüft.

























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